A. Perneczky and R. Reisch, in collaboration with M. Tschabitscher, offer a detailed systematic overview of the different approaches for minimally invasive craniotomies. After a description of the historical development of the particular craniotomy, each chapter illustrates the anatomical construction of the target region and the surgical approach itself with artistic illustrations and photographs of human cadaver dissections. Concentrating on surgical practice, patient positioning, anatomical orientation, the stages of the surgical approach, potential errors with their consequences, and important tips and tricks are discussed in detail, providing instructions for everyday use.