This book constitutes the proceedings of the 23nd International Conference on Web Information Systems Engineering, WISE 2021, held in Biarritz, France, in November 2022. The 31 full, 13 short and 3 demo papers were carefully reviewed and selected from 94 submissions. The papers are organized in the following topical sections: Social Media, Spatial & Temporal Issues, Query Processing & Information Extraction, Architecture and Performance, Graph Data Management, Security & Privacy, Information Retrieval & Text Processing, Reinforcement Learning, Learning & Optimization, Spatial Data Processing, Recommendation, Neural Networks, and Demo Papers.