This book constitutes the refereed proceedings of the 15th Mexican Conference on Pattern Recognition, MCPR 2023, held in Tepic, Mexico, during June 21–24, 2023. The 30 full papers presented in this book were carefully reviewed and selected from 61 submissions. The papers are divided into the following topical sections: pattern recognition and machine learning techniques; deep learning and neural networks; medical applications of pattern recognition; language processing and recognition; and industrial applications of pattern recognition.